FGF-8 Recombinant Protein

CATALOG NUMBER: 40-171

Specifications
source-species:
E. coli
Species:
Human, Mouse
source-species:
E. coli
Recombinant Protein Sequence:
MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR
Biological Activity:
Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 5 ng/ml, corresponding to a specific activity of ≥ 2 x 105 units/mg.
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized FGF-8 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted FGF-8 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing FGF-8 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
FGF8
Additional Names:
HH6, AIGF, KAL6, FGF-8, HBGF-8, Fibroblast growth factor 8, Androgen-induced growth factor
Protein Accession Number:
NP_001193318.1
Protein Gi Number:
329755303
Ncbi Gene Id Number:
2253
Background:
FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.4 kDa protein consisting of 193 amino acid residues.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-171

List Size:
0.005 mg, 0.025 mg

List Price:

Price range: $215.00 through $323.00

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