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Western blot analysis of extracts from HepG2 cells using FGFR1/2 (Phospho-Tyr463/466) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HepG2 cells using FGFR1/2 (Phospho-Tyr463/466) Antibody. The lane on the right is treated with the antigen-specific peptide.

FGFR1/2 (phospho Tyr463/466) Antibody

CATALOG NUMBER: 79-883

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p)-E-L) derived from Human FGFR1/2.
Conjugate:
Unconjugated
Tested Applications:
WB
Specificity:
The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466.
Predicted Molecular Weight:
91 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
FGFR1, FGFR2
Additional Names:
BFGFR, CEK, FLG, CD331, FLT2
Protein Accession Number:
NP_075598.2
Protein Gi Number:
291327489
Ncbi Gene Id Number:
2260;2263
Background:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
Background Reference 1:
Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990).
Background Reference 2:
Dionne C.A., EMBO J. 9:2685-2692(1990).
Background Reference 3:
Johnson D.E., Mol. Cell. Biol. 10:4728-4736(1990).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-883

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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