FIP1L1 Antibody

CATALOG NUMBER: 29-473

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FIP1L1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
FIP1L1 antibody can be used for detection of FIP1L1 by ELISA at 1:62500. FIP1L1 antibody can be used for detection of FIP1L1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
65 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store FIP1L1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
FIP1L1
Additional Names:
FIP1L1, DKFZp586K0717, FLJ33619, Rhe, FIP1, hFip1
Protein Accession Number:
NP_112179
Protein Gi Number:
40254978
Ncbi Gene Id Number:
81608
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. FIP1L1 contributes to poly (A) site recognition and stimulates poly (A) addition. It binds to U-rich RNA sequence elements surrounding the poly (A) site. FIP1L1 may act to tether poly (A) polymerase to the CPSF complex.
Background Reference 1:
Zhao, X., (2005) J. Virol. 79 (7), 4270-4288.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-473

List Size:
100 ul

List Price:

$519.00

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