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Western blot analysis of lysate from human brain tissue lysate, using FKTN Antibody at 1:1000 at each lane.
FKTN Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis of lysate from human brain tissue lysate, using FKTN Antibody at 1:1000 at each lane.

FKTN Antibody

CATALOG NUMBER: 56-645

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This FKTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human FKTN.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
54 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FKTN
Additional Names:
Fukutin, 2---, Fukuyama-type congenital muscular dystrophy protein, FKTN, FCMD
Protein Accession Number:
O75072
Ncbi Gene Id Number:
2218
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a putativetransmembrane protein that is localized to the cis-Golgicompartment, where it may be involved in the glycosylation ofalpha-dystroglycan in skeletal muscle. The encoded protein isthought to be a glycosyltransferase and could play a role in braindevelopment. Defects in this gene are a cause of Fukuyama-typecongenital muscular dystrophy (FCMD), Walker-Warburg syndrome(WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilatedcardiomyopathy type 1X (CMD1X). Alternatively spliced transcriptvariants have been found for this gene.
Background Reference 1:
Lim, B.C., et al. Neuromuscul. Disord. 20(8):524-530(2010)
Background Reference 2:
Saredi, S., et al. Muscle Nerve 39(6):845-848(2009)
Background Reference 3:
Chang, W., et al. Prenat. Diagn. 29(6):560-569(2009)
Background Reference 4:
Mercuri, E., et al. Neurology 72(21):1802-1809(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-645

List Size:
400 ul

List Price:

$495.00

Datasheet
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