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FLIP Antibody [Dave-2]

CATALOG NUMBER: XA-1008

Clonality:
Monoclonal
Tested Applications:
IP, WB
Host Species:
Rat
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant human FLIP (aa 1-480).
Conjugate:
Unconjugated
Tested Applications:
IP, WB
Application Note:
Immunoprecipitation: (1-2ug/ml) . Western Blot: (1-5ug/ml) . Optimal conditions must be determined individually for each application.
Specificity:
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP.
Clonality:
Monoclonal
Isotype:
IgG2a
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
CFLAR
Additional Names:
I-FLICE; CLARP; CASPER; Usurpin, CASH; FLAME-1
Protein Accession Number:
2253679
Protein Gi Number:
AAC51622
Ncbi Gene Id Number:
8837
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XA-1008

List Size:
100 ug

List Price:

$577.00

Datasheet
Shipping Info

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