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Fn14 Recombinant Protein

CATALOG NUMBER: 90-242

Specifications
source-species:
HEK293 cells
Species:
Human, Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water.
Concentration:
1mg/ml after reconstitution.
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
TNFRSF12A
Additional Names:
Tumor Necrosis Factor Receptor Superfamily Member 12A, FGF-inducible 14, Tweak-receptor, CD266, TNFRSF12A
Protein Accession Number:
Q9NP84
Protein Gi Number:
7706186
Ncbi Gene Id Number:
51330
Background:
TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK–Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-242

List Size:
50 ug

List Price:

$423.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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