FNTA Antibody

CATALOG NUMBER: 59-614

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human FNTA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FNTA
Additional Names:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA
Protein Accession Number:
P49354
Protein Gi Number:
1346694
Ncbi Gene Id Number:
2339
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Prenyltransferases can attach either a farnesyl group or ageranylgeranyl group in thioether linkage to the cysteine residueof proteins with a C-terminal CAAX box. CAAXgeranylgeranyltransferase and CAAX farnesyltransferase areheterodimers that share the same alpha subunit but have differentbeta subunits. This gene encodes the alpha subunit of thesetransferases. Alternative splicing results in multiple transcriptvariants. Related pseudogenes have been identified on chromosomes11 and 13.
Background Reference 1:
Lipkin, S.M., et al. Cancer Prev Res (Phila Pa) 3(5):597-603(2010)
Background Reference 2:
Fontaine-Bisson, B., et al. J. Mol. Med. 88(2):193-201(2010)
Background Reference 3:
Zhou, J., et al. J. Biol. Chem. 284(15):9648-9655(2009)
Background Reference 4:
Veluthakal, R., et al. Diabetes 56(1):204-210(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-614

List Size:
400 ul

List Price:

$495.00

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