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Western blot analysis in MDA-MB453,NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453,NCI-H460 cell line lysates (35ug/lane).

FOLR2 Antibody

CATALOG NUMBER: 58-204

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
29 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FOLR2
Additional Names:
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Protein Accession Number:
P14207
Protein Gi Number:
116241366
Ncbi Gene Id Number:
2350
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the folatereceptor (FOLR) family, and these genes exist in a cluster onchromosome 11. Members of this gene family have a high affinity forfolic acid and for several reduced folic acid derivatives, and theymediate delivery of 5-methyltetrahydrofolate to the interior ofcells. This protein has a 68% and 79% sequence homology with theFOLR1 and FOLR3 proteins, respectively. Although this protein wasoriginally thought to be specific to placenta, it can also exist inother tissues, and it may play a role in the transport ofmethotrexate in synovial macrophages in rheumatoid arthritispatients. Multiple transcript variants that encode the same proteinhave been found for this gene.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(8):689-694(2010)
Background Reference 3:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 4:
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-204

List Size:
400 ul

List Price:

$495.00

Datasheet
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