FOS Antibody

CATALOG NUMBER: 31-160

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOS.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
FOS antibody can be used for detection of FOS by ELISA at 1:312500. FOS antibody can be used for detection of FOS by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
41 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store FOS antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
FOS
Additional Names:
FOS, p55, AP-1, C-FOS
Protein Accession Number:
NP_005243
Protein Gi Number:
4885241
Ncbi Gene Id Number:
2353
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Background Reference 1:
Pan, X., et al., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1052-1058.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-160

List Size:
100 ul

List Price:

$473.00

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