FOXC1 Antibody

CATALOG NUMBER: 27-542

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXC1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
FOXC1 antibody can be used for detection of FOXC1 by ELISA at 1:62500. FOXC1 antibody can be used for detection of FOXC1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
57 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store FOXC1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
FOXC1
Additional Names:
FOXC1, ARA, IGDA, IHG1, FKHL7, IRID1, RIEG3, FREAC3, FREAC-3
Protein Accession Number:
NP_001444
Protein Gi Number:
119395716
Ncbi Gene Id Number:
2296
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
Background Reference 1:
Mortemousque, B., et al., (2004) Arch. Ophthalmol. 122 (10), 1527-1533.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-542

List Size:
100 ul

List Price:

$473.00

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