FRS2 Antibody

CATALOG NUMBER: 60-155

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the Central region of human FRS2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
57 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FRS2
Additional Names:
Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1, FRS2
Protein Accession Number:
Q8WU20
Protein Gi Number:
209572769
Ncbi Gene Id Number:
10818
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Background Reference 1:
Zhou, W., et al. Cell Res. 19(10):1165-1177(2009)
Background Reference 2:
Cha, J.Y., et al. J. Biol. Chem. 284(10):6227-6240(2009)
Background Reference 3:
Li, M., et al. J. Dermatol. Sci. 53(3):182-191(2009)
Background Reference 4:
Turner, S.T., et al. Hypertension 52(2):359-365(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-155

List Size:
400 ul

List Price:

$495.00

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