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Western blot analysis of extracts from HuvEc cells (Lane 2) and JK cells (Lane 3), using FRS2 (Phospho-Tyr436) Antibody. The lane on the left is treated with antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using FRS2 (Phospho-Tyr436) antibody (left) or the same antibody preincubated with blocking peptide (right).
Western blot analysis of extracts from HuvEc cells (Lane 2) and JK cells (Lane 3), using FRS2 (Phospho-Tyr436) Antibody. The lane on the left is treated with antigen-specific peptide.

FRS2 (phospho Tyr436) Antibody

CATALOG NUMBER: 79-880

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
FRS2 (phospho Tyr436) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 436 (L-N-Y (p)-I-Q) derived from Human FRS2 .
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of FRS2 only when phosphorylated at tyrosine 436.
Predicted Molecular Weight:
65 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
FRS2
Additional Names:
SNT-1, SNT2, FGFR signalling adaptor
Protein Accession Number:
NP_001036020.1
Protein Gi Number:
110347408
Ncbi Gene Id Number:
10818
Background:
FRS2 is an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.
Background Reference 1:
Xu H., J. Biol. Chem. 273:17987-17990(1998).
Background Reference 2:
Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).
Background Reference 3:
Dhalluin C., Mol. Cell 6:921-929(2000).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-880

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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