FTO Antibody [FT62-6]

CATALOG NUMBER: 36-084

Clonality:
Monoclonal
Tested Applications:
ELISA, IHC, IP, WB
Host Species:
Mouse
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Mouse
Immunogen:
Recombinant human FTO.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, IP, WB
Application Note:
ELISA: (direct and indirect: 1:2,000-1:5,000). Immunohistochemistry: (paraffin sections (1:100-1:500)). Immunoprecipitation: (5ug/ml per sample in a final reaction volume of 500-1000ul). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Specificity:
Recognizes mouse FTO. Weakly cross-reacts with human FTO. Does not cross-react with rat FTO.
Clonality:
Monoclonal
Isotype:
IgG1, kappa
physical-state:
Liquid
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
Fto
Additional Names:
Fat Mass and Obesity-associated Protein; FATSO
Protein Accession Number:
81873739
Protein Gi Number:
Q8BGW1
Ncbi Gene Id Number:
26383
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-084

List Size:
100 ug

List Price:

$446.00

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