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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

FUSIP1 Antibody

CATALOG NUMBER: 59-189

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This FUSIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human FUSIP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
31 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SRSF10
Additional Names:
Serine/arginine-rich splicing factor 10, 40 kDa SR-repressor protein, SRrp40, FUS-interacting serine-arginine-rich protein 1, Splicing factor SRp38, Splicing factor, arginine/serine-rich 13A, TLS-associated protein with Ser-Arg repeats, TASR, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein, TLS-associated SR protein, SRSF10, FUSIP1, FUSIP2, SFRS13A, TASR
Protein Accession Number:
O75494
Ncbi Gene Id Number:
10772
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene product is a member of the serine-arginine (SR)family of proteins, which is involved in constitutive and regulatedRNA splicing. Members of this family are characterized byN-terminal RNP1 and RNP2 motifs, which are required for binding toRNA, and multiple C-terminal SR/RS repeats, which are important inmediating association with other cellular proteins. This proteincan influence splice site selection of adenovirus E1A pre-mRNA. Itinteracts with the oncoprotein TLS, and abrogates the influence ofTLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes.Alternative splicing of this gene results in multiple transcriptvariants encoding different isoforms. In addition, transcriptvariants utilizing alternative polyA sites exist.
Background Reference 1:
Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)
Background Reference 2:
Ling, I.F., et al. Hum. Mutat. 31(6):702-709(2010)
Background Reference 3:
Shi, Y., et al. Mol. Cell 28(1):79-90(2007)
Background Reference 4:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-189

List Size:
400 ul

List Price:

$495.00

Datasheet
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