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Western Blot at 1:1000 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 ug per lane.

FXN Antibody

CATALOG NUMBER: 60-803

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
23 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FXN
Additional Names:
Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin(56-210), m56-FXN, Frataxin(78-210), d-FXN, m78-FXN, Frataxin mature form, Frataxin(81-210), m81-FXN, FXN, FRDA, X25
Protein Accession Number:
Q16595
Ncbi Gene Id Number:
2395
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This nuclear gene encodes a mitochondrial protein whichbelongs to FRATAXIN family. The protein functions in regulatingmitochondrial iron transport and respiration. The expansion ofintronic trinucleotide repeat GAA results in Friedreich ataxia.Alternative splicing results in multiple transcript variants.
Background Reference 1:
Tsai, C.L., et al. Biochemistry 49(43):9132-9139(2010)
Background Reference 2:
Thierbach, R., et al. Biochem. J. 432(1):165-172(2010)
Background Reference 3:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 4:
Marino, T.C., et al. Clin. Genet. 77(6):598-600(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-803

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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