FXR1 Antibody

CATALOG NUMBER: 60-914

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Rat
Immunogen:
This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
70 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FXR1
Additional Names:
Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1
Protein Accession Number:
P51114
Protein Gi Number:
189047132
Ncbi Gene Id Number:
8087
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is an RNA binding proteinthat interacts with the functionally-similar proteins FMR1 andFXR2. These proteins shuttle between the nucleus and cytoplasm andassociate with polyribosomes, predominantly with the 60S ribosomalsubunit. Three transcript variants encoding different isoforms havebeen found for this gene.
Background Reference 1:
Coffee, R.L. Jr., et al. Dis Model Mech(7-8), 471-485 (2010) :
Background Reference 2:
Darnell, J.C., et al. Hum. Mol. Genet. 18(17):3164-3177(2009)
Background Reference 3:
Purcell, S.M., et al. Nature 460(7256):748-752(2009)
Background Reference 4:
Davidovic, L., et al. J. Med. Genet. 45(10):679-685(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-914

List Size:
400 ul

List Price:

$495.00

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