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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

FZD7 Antibody

CATALOG NUMBER: 59-598

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
64 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FZD7
Additional Names:
Frizzled-7, Fz-7, hFz7, FzE3, FZD7
Protein Accession Number:
O75084
Ncbi Gene Id Number:
8324
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Members of the 'frizzled' gene family encode7-transmembrane domain proteins that are receptors for Wntsignaling proteins. The FZD7 protein contains an N-terminal signalsequence, 10 cysteine residues typical of the cysteine-richextracellular domain of Fz family members, 7 putative transmembranedomains, and an intracellular C-terminal tail with a PDZdomain-binding motif. FZD7 gene expression may downregulate APCfunction and enhance beta-catenin-mediated signals in poorlydifferentiated human esophageal carcinomas.
Background Reference 1:
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Background Reference 2:
Vincan, E., et al. Dev. Dyn. 239(1):311-317(2010)
Background Reference 3:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 4:
Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-598

List Size:
400 ul

List Price:

$495.00

Datasheet
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