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Antibody used in WB on Human HepG2 at 1.25 ug/ml.
Antibody used in WB on Human HepG2 at 1.25 ug/ml.

G22P1 Antibody

CATALOG NUMBER: 28-005

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human G22P1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
G22P1 antibody can be used for detection of G22P1 by ELISA at 1:62500. G22P1 antibody can be used for detection of G22P1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
70 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store G22P1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
XRCC6
Additional Names:
G22P1, ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Protein Accession Number:
NP_001460
Protein Gi Number:
4503841
Ncbi Gene Id Number:
2547
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Background Reference 1:
Sawchuk, D.J., et al., (2004) J. Biol. Chem. 279 (28), 29821-29831.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-005

List Size:
100 ul

List Price:

$473.00

Datasheet
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