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Western blot analysis in human placenta tissue lysates (35ug/lane).
Western blot analysis in human placenta tissue lysates (35ug/lane).

GAB3 Antibody

CATALOG NUMBER: 58-446

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human GAB3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
66 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GAB3
Additional Names:
GRB2-associated-binding protein 3, GRB2-associated binder 3, Growth factor receptor bound protein 2-associated protein 3, GAB3
Protein Accession Number:
Q8WWW8
Protein Gi Number:
74716251
Ncbi Gene Id Number:
139716
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GAB3 is a member of the GRB2-associated bindingprotein gene family. These proteins are scaffolding/dockingproteins that are involved in several growth factor and cytokinesignaling pathways, and they contain a pleckstrin homology domain,and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. Theprotein encoded by this gene facilitates macrophagedifferentiation. Two transcript variants encoding differentisoforms have been found for this gene.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 3:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 4:
Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-446

List Size:
400 ul

List Price:

$495.00

Datasheet
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