GABPA Antibody

CATALOG NUMBER: 57-435

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GABPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the Central region of human GABPA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
51 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GABPA
Additional Names:
GA-binding protein alpha chain, GABP subunit alpha, Nuclear respiratory factor 2 subunit alpha, Transcription factor E4TF1-60, GABPA, E4TF1A
Protein Accession Number:
Q06546
Protein Gi Number:
729553
Ncbi Gene Id Number:
2551
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes one of three GA-binding proteintranscription factor subunits which functions as a DNA-bindingsubunit. Since this subunit shares identity with a subunit encodingthe nuclear respiratory factor 2 gene, it is likely involved inactivation of cytochrome oxidase expression and nuclear control ofmitochondrial function. This subunit also shares identity with asubunit constituting the transcription factor E4TF1, responsiblefor expression of the adenovirus E4 gene. Because of itschromosomal localization and ability to form heterodimers withother polypeptides, this gene may play a role in the Down Syndromephenotype. Two transcript variants encoding the same protein havebeen found for this gene.
Background Reference 1:
Henderson, A.J., et al. Thorax 65(10):897-902(2010)
Background Reference 2:
Eynon, N., et al. Physiol. Genomics 41(1):78-81(2010)
Background Reference 3:
Levy, S., et al. IUBMB Life 62(3):237-246(2010)
Background Reference 4:
Kim, Y.R., et al. J. Pathol. 220(4):446-451(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-435

List Size:
400 ul

List Price:

$495.00

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