GABRB1 (Ab 434) Antibody

CATALOG NUMBER: 79-582

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
GABRB1 (Ab-434) antibody was raised against a peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total GABRB1 protein.
Predicted Molecular Weight:
54 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
GABRB1
Additional Names:
GABA(A) receptor, GABA(A)R beta-1, GBRB1, GABA-RB
Protein Accession Number:
NP_000803.2
Protein Gi Number:
194097327
Ncbi Gene Id Number:
2560
Background:
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.
Background Reference 1:
Collins AL, et al. (2006) Neurogenetics ;7 (3): 167-174. Ma DQ, et al. (2005) Am J Hum Genet ;77 (3): 377-388. Edenberg HJ, et al. (2004) Am J Hum Genet ;74 (4): 705-714.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-582

List Size:
0.1 mg

List Price:

$370.00

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