GABRB2 Antibody

CATALOG NUMBER: 57-799

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This GABRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-374 amino acids from the C-terminal region of human GAB_2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:500
Predicted Molecular Weight:
59 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GABRB2
Additional Names:
Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2, GABRB2
Protein Accession Number:
P47870
Protein Gi Number:
292495010
Ncbi Gene Id Number:
2561
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The gamma-aminobutyric acid (GABA) A receptor is amultisubunit chloride channel that mediates the fastest inhibitorysynaptic transmission in the central nervous system. This geneencodes GABA A receptor, beta 2 subunit. It is mapped to chromosome5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2subunits of the GABA A receptor. Alternative splicing of this genegenerates 2 transcript variants, differing by a 114 bp insertion.
Background Reference 1:
Lo, W.Y., et al. J. Biol. Chem. 285(41):31348-31361(2010)
Background Reference 2:
Green, E.K., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (7), 1347-1349 (2010) :
Background Reference 3:
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 4:
Chen, J., et al. Biochem. Soc. Trans. 37 (PT 6), 1415-1418 (2009) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-799

List Size:
400 ul

List Price:

$495.00

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