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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

GAD1 Antibody

CATALOG NUMBER: 55-719

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 514-543 amino acids from the C-terminal region of human GAD1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
67 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GAD1
Additional Names:
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD1, GAD, GAD67
Protein Accession Number:
Q99259
Protein Gi Number:
1352213
Ncbi Gene Id Number:
2571
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantigen and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxinedependency with seizures. Alternative splicing of this gene resultsin two products, the predominant 67-kD form and a less-frequent25-kD form.
Background Reference 1:
Lanoue, A.C., et al. Exp. Neurol. 226(1):207-217(2010)
Background Reference 2:
Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010) :
Background Reference 3:
Terranova, C., et al. Alcohol 44(5):407-413(2010)
Background Reference 4:
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-719

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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