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Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.

GADD45B Antibody

CATALOG NUMBER: 30-398

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GADD45B.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
GADD45B antibody can be used for detection of GADD45B by ELISA at 1:1562500. GADD45B antibody can be used for detection of GADD45B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
18 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store GADD45B antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
GADD45B
Additional Names:
GADD45B, DKFZP566B133, GADD45BETA, MYD118
Protein Accession Number:
NP_056490
Protein Gi Number:
86991436
Ncbi Gene Id Number:
4616
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background Reference 1:
Tornatore, L., (2008) J. Mol. Biol. 378 (1), 97-111.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-398

List Size:
100 ul

List Price:

$519.00

Datasheet
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