GAMT Antibody

CATALOG NUMBER: 29-621

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GAMT.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
GAMT antibody can be used for detection of GAMT by ELISA at 1:62500. GAMT antibody can be used for detection of GAMT by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
26 kDa, 29 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store GAMT antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
GAMT
Additional Names:
GAMT, PIG2, TP53I2, CCDS2, HEL-S-20
Protein Accession Number:
NP_000147
Protein Gi Number:
4503909
Ncbi Gene Id Number:
2593
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
Background Reference 1:
Komoto, J., (1999) Acta Crystallogr. D Biol. Crystallogr. 55 (11), 1928-1929.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-621

List Size:
100 ul

List Price:

$519.00

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