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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

GATM Antibody

CATALOG NUMBER: 60-678

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rat
Immunogen:
This GATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GATM
Additional Names:
Glycine amidinotransferase, mitochondrial, L-arginine:glycine amidinotransferase, Transamidinase, GATM, AGAT
Protein Accession Number:
P50440
Protein Gi Number:
1730201
Ncbi Gene Id Number:
2628
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a mitochondrial enzyme that belongs tothe amidinotransferase family. This enzyme is involved in creatinebiosynthesis, whereby it catalyzes the transfer of a guanido groupfrom L-arginine to glycine, resulting in guanidinoacetic acid, theimmediate precursor of creatine. Mutations in this gene causearginine:glycine amidinotransferase deficiency, an inborn error ofcreatine synthesis characterized by mental retardation, languageimpairment, and behavioral disorders.
Background Reference 1:
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Background Reference 2:
Kottgen, A., et al. Nat. Genet. 41(6):712-717(2009)
Background Reference 3:
Lion-Francois, L., et al. Neurology 67(9):1713-1714(2006)
Background Reference 4:
Cullen, M.E., et al. Circulation 114 (1 SUPPL), I16-I20 (2006) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-678

List Size:
400 ul

List Price:

$495.00

Datasheet
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