GC Antibody

CATALOG NUMBER: 61-272

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 442-473 amino acids from human GC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GC
Additional Names:
Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC
Protein Accession Number:
P02774
Protein Gi Number:
139641
Ncbi Gene Id Number:
2638
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Background Reference 1:
Cooke N.E.,et al.J. Clin. Invest. 76:2420-2424(1985).
Background Reference 2:
Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7994-7998(1985).
Background Reference 3:
Braun A.,et al.Biochim. Biophys. Acta 1216:385-394(1993).
Background Reference 4:
Witke W.F.,et al.Genomics 16:751-754(1993).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-272

List Size:
200 ul

List Price:

$495.00

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