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Antibody used in WB on Human Liver at 0.2-1 ug/ml.
Antibody used in WB on Human Liver at 0.2-1 ug/ml.

GCHFR Antibody

CATALOG NUMBER: 25-878

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GCHFR.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
GCHFR antibody can be used for detection of GCHFR by ELISA at 1:312500. GCHFR antibody can be used for detection of GCHFR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Predicted Molecular Weight:
10 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store GCHFR antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
GCHFR
Additional Names:
GCHFR, GFRP, HsT16933, MGC138467, MGC138469, P35
Protein Accession Number:
NP_005249
Protein Gi Number:
4885257
Ncbi Gene Id Number:
2644
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
Background Reference 1:
Ohta, E., (2006) Arch. Neurol. 63 (11), 1605-1610.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-878

List Size:
100 ul

List Price:

$519.00

Datasheet
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