GCNT2 Antibody

CATALOG NUMBER: 59-898

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the Central region of human GCNT2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
46 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GCNT2
Additional Names:
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Protein Accession Number:
Q8N0V5
Protein Gi Number:
298351849
Ncbi Gene Id Number:
2651
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the enzyme responsible for formation ofthe blood group I antigen. The i and I antigens are distinguishedby linear and branched poly-N-acetyllactosaminoglycans,respectively. The encoded protein is the I-branching enzyme, abeta-1,6-N-acetylglucosaminyltransferase responsible for theconversion of fetal i antigen to adult I antigen in erythrocytesduring embryonic development. Mutations in this gene have beenassociated with adult i blood group phenotype. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.
Background Reference 1:
Twu, Y.C., et al. Blood 110(13):4526-4534(2007)
Background Reference 2:
Wang, L., et al. Biochem. Biophys. Res. Commun. 331(4):958-963(2005)
Background Reference 3:
Pras, E., et al. Invest. Ophthalmol. Vis. Sci. 45(6):1940-1945(2004)
Background Reference 4:
Inaba, N., et al. Blood 101(7):2870-2876(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-898

List Size:
400 ul

List Price:

$495.00

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