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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
GDF5 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

GDF5 Antibody

CATALOG NUMBER: 56-193

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human GDF5.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GDF5
Additional Names:
Growth/differentiation factor 5, GDF-5, Bone morphogenetic protein 14, BMP-14, Cartilage-derived morphogenetic protein 1, CDMP-1, Lipopolysaccharide-associated protein 4, LAP-4, LPS-associated protein 4, Radotermin, GDF5, BMP14, CDMP1
Protein Accession Number:
P43026
Protein Gi Number:
20141384
Ncbi Gene Id Number:
8200
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the bonemorphogenetic protein (BMP) family and the TGF-beta superfamily.This group of proteins is characterized by a polybasic proteolyticprocessing site which is cleaved to produce a mature proteincontaining seven conserved cysteine residues. The members of thisfamily are regulators of cell growth and differentiation in bothembryonic and adult tissues. Mutations in this gene are associatedwith acromesomelic dysplasia, Hunter-Thompson type; brachydactyly,type C; and chondrodysplasia, Grebe type. These associationsconfirm that the gene product plays a role in skeletal development.
Background Reference 1:
Posthumus, M., et al. Rheumatology (Oxford) 49(11):2090-2097(2010)
Background Reference 2:
Rouault, K., et al. Osteoarthr. Cartil. 18(9):1144-1149(2010)
Background Reference 3:
Zintzaras, E., et al. Am. J. Epidemiol. 171(8):851-858(2010)
Background Reference 4:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-193

List Size:
400 ul

List Price:

$495.00

Datasheet
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