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Antibody is used in Western blot to detect GDF5 in A549 cell lysate.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GDF5 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Antibody is used in Western blot to detect GDF5 in A549 cell lysate.

GDF5 Antibody

CATALOG NUMBER: 61-070

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human GDF5.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GDF5
Additional Names:
Growth/differentiation factor 5, GDF-5, Bone morphogenetic protein 14, BMP-14, Cartilage-derived morphogenetic protein 1, CDMP-1, Lipopolysaccharide-associated protein 4, LAP-4, LPS-associated protein 4, Radotermin, GDF5, BMP14, CDMP1
Protein Accession Number:
P43026
Protein Gi Number:
20141384
Ncbi Gene Id Number:
8200
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Background Reference 1:
Kusafuka, K., et al., Virchows Arch. 442(5):482-490 (2003).
Background Reference 2:
Faiyaz-Ul-Haque, M., et al., Am. J. Med. Genet. 111(1):31-37 (2002).
Background Reference 3:
Everman, D.B., et al., Am. J. Med. Genet. 112(3):291-296 (2002).
Background Reference 4:
Faiyaz-Ul-Haque, M., et al., Clin. Genet. 61(6):454-458 (2002).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-070

List Size:
400 ul

List Price:

$495.00

Datasheet
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