GEMIN4 Antibody

CATALOG NUMBER: 60-915

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
120 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GEMIN4
Additional Names:
Gem-associated protein 4, Gemin-4, Component of gems 4, p97, GEMIN4
Protein Accession Number:
P57678
Protein Gi Number:
322510030
Ncbi Gene Id Number:
50628
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene is part of a large complexlocalized to the cytoplasm, nucleoli, and to discrete nuclearbodies called Gemini bodies (gems). The complex functions inspliceosomal snRNP assembly in the cytoplasm, and regeneratesspliceosomes required for pre-mRNA splicing in the nucleus. Theencoded protein directly interacts with a DEAD box protein andseveral spliceosome core proteins. Alternatively spliced transcriptvariants have been described, but their biological validity has notbeen determined.
Background Reference 1:
Kim, J.S., et al. Mol. Carcinog. 49(10):913-921(2010)
Background Reference 2:
Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
Background Reference 3:
Boni, V., et al. Pharmacogenomics J. (2010) In press :
Background Reference 4:
Clague, J., et al. Mol. Carcinog. 49(2):183-189(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-915

List Size:
400 ul

List Price:

$495.00

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