Gevokizumab binds with IL1B

Recombinant

Gevokizumab (IL1B) – Research Grade Biosimilar

CATALOG NUMBER: 10-129

Clonality:

Recombinant Monoclonal

Conjugate:

Unconjugated

Specifications

source-species:

CHO cells

source-species:

CHO cells

Immunogen:

Humanized / IL1B [Homo sapiens]

Conjugate:

Unconjugated

Advanced Validation

Properties

Purification:

>95%

Clonality:

Recombinant Monoclonal

Isotype:

IgG2-kappa

Buffer:

PBS buffer pH7.5

Concentration:

batch dependent

Storage Conditions:

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Additional Info

Additional Names:

XOMA 052, IL1B, IL1B

User Note:

Optimal dilutions for each application to be determined by the researcher.

Background

Background:

Gevokizumab has been used in trials studying the treatment of Acne Vulgaris,Osteoarthritis, Behcet's Uveitis,Pyoderma Gangrenosum, and Behcet's Disease Uveitis,among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states.It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors.

Citations

Set Contents

Disclaimer

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

View product citations for catalog number 10-129 on CiteAb

CATALOG NUMBER:

10-129

List Size:

0.1 mg

List Price:

$515.00

Datasheet

Shipping Info

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Gevokizumab (IL1B) – Research Grade Biosimilar

Clonality:

Conjugate:

source-species:

source-species:

Immunogen:

Conjugate:

Purification:

Clonality:

Isotype:

Buffer:

Concentration:

Storage Conditions:

Additional Names:

User Note:

Background:

Disclaimer:

List Size:

Shipping Info

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