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Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.
Antibody used in WB on Human Jurkat cells at 1 ug/ml.
Antibody used in IHC on Human Adult Liver at 1:100.
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.

GGCX Antibody

CATALOG NUMBER: 25-950

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GGCX.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
GGCX antibody can be used for detection of GGCX by ELISA at 1:1562500. GGCX antibody can be used for detection of GGCX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1219 - MCF7 Cell Lysate
Predicted Molecular Weight:
87 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store GGCX antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
GGCX
Additional Names:
GGCX, FLJ26629, VKCFD1
Protein Accession Number:
NP_000812
Protein Gi Number:
21361163
Ncbi Gene Id Number:
2677
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).
Background Reference 1:
Rieder, M.J., (2007) J. Thromb. Haemost. 5 (11), 2227-2234.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-950

List Size:
100 ul

List Price:

$519.00

Datasheet
Shipping Info

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