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Western Blot at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 ug per lane.

GIPR Antibody

CATALOG NUMBER: 62-949

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-136 amino acids from the Central region of human GIPR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GIPR
Additional Names:
Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, GIPR
Protein Accession Number:
P48546
Protein Gi Number:
1346133
Ncbi Gene Id Number:
2696
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
Background Reference 1:
Herbach,N. Am. J. Physiol. Renal Physiol. 296 (4), F819-F829 (2009)
Background Reference 2:
Rudovich,N., Kaiser,S. Regul. Pept. 142 (3), 138-145 (2007)
Background Reference 3:
Nitz,I., Fisher,E. Mol Nutr Food Res 51 (8), 1046-1052 (2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-949

List Size:
400 ul

List Price:

$495.00

Datasheet
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