Girdin (phospho Ser1417) Antibody

CATALOG NUMBER: 79-914

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
Girdin (phospho Ser1417) antibody was raised against a peptide sequence around phosphorylation site of Serine 417 (L-E-M (p)-A-Q) derived from Human Girdin .
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of Girdin only when phosphorylated at serine 1417.
Predicted Molecular Weight:
216 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CCDC88A
Additional Names:
APE, GIV, GRDN, HkRP1, KIAA1212
Protein Accession Number:
NP_060554.3
Protein Gi Number:
50897852
Ncbi Gene Id Number:
55704
Background:
girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.
Background Reference 1:
Enomoto A., Dev. Cell 9:389-402(2005).
Background Reference 2:
Simpson F., Traffic 6:442-458(2005).
Background Reference 3:
Hillier L.W., Nature 434:724-731(2005).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-914

List Size:
0.1 mg

List Price:

$376.00

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