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Immobilized Mouse GITR, His Tag at 10 ug/mL (100 uL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 ug/mL.
Immobilized Mouse GITR, His Tag at 10 ug/mL (100 uL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 ug/mL.

GITR Ligand Recombinant Protein

CATALOG NUMBER: 96-999

Tested Applications:
ELISA, WB
Specifications
Source Species:
HEK293 cells
Species:
Mouse
Source Species:
HEK293 cells
Recombinant Protein Sequence:
Thr 47 - Ser 173
Fusion Tag:
Fc Tag
Tested Applications:
ELISA, WB
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Predicted Molecular Weight:
41.4 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Mouse GITR, His Tag at 10 ug/mL (100 uL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 ug/mL.
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Physical State:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
GITR Ligand
Additional Names:
TNFSF18,AITRL,TL6,hGITRL,GITR Ligand
Protein Accession Number:
AAO89011
Ncbi Gene Id Number:
294099
Background:
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
Background Reference 1:
Tuyaerts S., et al., 2007, J. Leukoc. Biol. 82:93-105.
Background Reference 2:
Chattopadhyay K., et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104:19452-19457.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-999

List Size:
0.1 mg

List Price:

$577.00

Datasheet
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