GJB1 Antibody

CATALOG NUMBER: 28-526

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJB1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
GJB1 antibody can be used for detection of GJB1 by ELISA at 1:312500. GJB1 antibody can be used for detection of GJB1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
31 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store GJB1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
GJB1
Additional Names:
GJB1, CMTX, CX32, CMTX1
Protein Accession Number:
NP_000157
Protein Gi Number:
4504005
Ncbi Gene Id Number:
2705
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes for a Connexin 32 protein. A large Charcot-Marie-Tooth disease family has been identified with a novel mutation in the Cx32 P2 promoter region at position -526bp. Cx32 mutants that are associated with a CNS phenotype may have toxic effects in oligodendrocytes.
Background Reference 1:
Dagli, M.L., et al., (2004) Carcinogenesis 25 (4), 483-492.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-526

List Size:
100 ul

List Price:

$473.00

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