Glypican 3 Recombinant Protein

CATALOG NUMBER: 96-804

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Cynomolgus monkey
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gln 25 - His 559
Fusion Tag:
Fc Tag
Tested Applications:
ELISA, WB
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Predicted Molecular Weight:
38.1 kDa and 49.4 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human FGF basic, Tag Free at 2 ug/mL (100 uL/well) can bind Cynomolgus Glypican 3, Fc Tag with a linear range of 4.8-19.5 ng/mL.
Purity:
>90% as determined by SDS-PAGE
physical-state:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
Glypican 3
Additional Names:
GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SGBS,SGBS1
Protein Accession Number:
XP_005594665.1
Ncbi Gene Id Number:
102137748
Background:
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Background Reference 1:
Davoodi J., et al., 2007, Proteomics 7:2300-2310.
Background Reference 2:
Veugelers M., et al., 2000, Hum. Mol. Genet. 9:1321-1328.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-804

List Size:
0.1 mg

List Price:

$515.00

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