GNAQ Antibody

CATALOG NUMBER: 57-538

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat, Xenopus
Immunogen:
This GNAQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human GNAQ.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GNAQ
Additional Names:
Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q, GNAQ, GAQ
Protein Accession Number:
P50148
Protein Gi Number:
251757492
Ncbi Gene Id Number:
2776
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This locus encodes a guanine nucleotide-binding protein.The encoded protein, an alpha subunit in the Gq class, couples aseven-transmembrane domain receptor to activation of phospolipaseC-beta. Mutations at this locus have been associated with problemsin platelet activation and aggregation. A related pseudogene existson chromosome 2.
Background Reference 1:
Dratviman-Storobinsky, O., et al. Invest. Ophthalmol. Vis. Sci. 51(12):6180-6182(2010)
Background Reference 2:
Crouthamel, M., et al. Mol. Pharmacol. 78(4):767-777(2010)
Background Reference 3:
Chillar, A., et al. Biochemistry 49(30):6365-6374(2010)
Background Reference 4:
Klenke, S., et al. Pharmacogenet. Genomics 20(8):476-484(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-538

List Size:
400 ul

List Price:

$495.00

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