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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

GNPTG Antibody

CATALOG NUMBER: 59-732

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GNPTG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-296 amino acids from the C-terminal region of human GNPTG.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
34 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GNPTG
Additional Names:
N-acetylglucosamine-1-phosphotransferase subunit gamma, GlcNAc-1-phosphotransferase subunit gamma, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma, GNPTG, C16orf27, GNPTAG
Protein Accession Number:
Q9UJJ9
Ncbi Gene Id Number:
84572
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the gamma sunbunit of theN-acetylglucosamine-1-phosphotransferase complex. This hexamericcomplex, composed of alpha, beta and gamma subunits, catalyzes thefirst step in synthesis of a mannose 6-phosphate lysosomalrecognition marker. This enzyme complex is necessary for targetingof lysosomal hydrolases to the lysosome. Mutations in the geneencoding the gamma subunit have been associated with mucolipidosisIIIC, also known as mucolipidosis III gamma.
Background Reference 1:
Kang, C., et al. N. Engl. J. Med. 362(8):677-685(2010)
Background Reference 2:
Qian, Y., et al. J. Biol. Chem. 285(5):3360-3370(2010)
Background Reference 3:
Pohl, S., et al. Am. J. Med. Genet.152A (1), 124-132 (2010) :
Background Reference 4:
Encarnacao, M., et al. Clin. Genet. 76(1):76-84(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-732

List Size:
400 ul

List Price:

$495.00

Datasheet
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