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Western blot analysis in mouse liver tissue lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in mouse liver tissue lysates (35ug/lane).

GPER Antibody

CATALOG NUMBER: 58-136

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This GPER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human GPER.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GPER1
Additional Names:
G-protein coupled estrogen receptor 1, Chemoattractant receptor-like 2, Flow-induced endothelial G-protein coupled receptor 1, FEG-1, G protein-coupled estrogen receptor 1, G-protein coupled receptor 30, GPCR-Br, IL8-related receptor DRY12, Lymphocyte-derived G-protein coupled receptor, LYGPR, Membrane estrogen receptor, mER, GPER1, CEPR, CMKRL2, DRY12, GPER, GPR30
Protein Accession Number:
Q99527
Protein Gi Number:
3023539
Ncbi Gene Id Number:
2852
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the G-protein coupled receptor 1family and encodes a multi-pass membrane protein that localizes tothe endoplasmic reticulum. The protein binds estrogen, resulting inintracellular calcium mobilization and synthesis ofphosphatidylinositol 3,4,5-trisphosphate in the nucleus. Thisprotein therefore plays a role in the rapid nongenomic signalingevents widely observed following stimulation of cells and tissueswith estrogen. Alternate transcriptional splice variants whichencode the same protein have been characterized. [provided byRefSeq].
Background Reference 1:
Patel, V.H., et al. Int. J. Mol. Med. 26(2):193-199(2010)
Background Reference 2:
Ignatov, A., et al. Breast Cancer Res. Treat. 123(1):87-96(2010)
Background Reference 3:
Li, Y., et al. Mol. Endocrinol. 24(5):969-980(2010)
Background Reference 4:
Kang, L., et al. Mol. Endocrinol. 24(4):709-721(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-136

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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