GPR39 Antibody

CATALOG NUMBER: 60-324

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GPR39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-407 amino acids from the C-terminal region of human GPR39.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
51 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GPR39
Additional Names:
G-protein coupled receptor 39, GPR39
Protein Accession Number:
O43194
Ncbi Gene Id Number:
2863
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
Background Reference 1:
Sharir, H., et al. J. Biol. Chem. 285(34):26097-26106(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Holst, B., et al. J. Biol. Chem. 285(6):3973-3985(2010)
Background Reference 4:
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-324

List Size:
400 ul

List Price:

$495.00

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