Granzyme B Recombinant Protein

CATALOG NUMBER: 91-607

Specifications

source-species:

HEK293 cells

Species:

Mouse

source-species:

HEK293 cells

Recombinant Protein Sequence:

Gly19-Ser247

Fusion Tag:

C-6 His tag

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Predicted Molecular Weight:

26.5 kD

Advanced Validation

Properties

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

physical-state:

Liquid

Buffer:

Supplied as a 0.2 um filtered solution of PBS,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Storage Conditions:

Store at -20°C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Additional Info

Ncbi Official Symbol:

Gzmb

Additional Names:

Granzyme B(G, H), CTLA-1, Cytotoxic cell protease 1, CCP1, Fragmentin-2, Gzmb, Ctla1

Protein Accession Number:

P04187

Protein Gi Number:

767957252

Ncbi Gene Id Number:

14939

Background

Background:

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Citations

Set Contents

Disclaimer

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:

Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

91-607

List Size:

0.05 mg

List Price:

$682.00

Datasheet

Shipping Info

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$35 Dry Ice Shipment fee may be required on some items.

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Granzyme B Recombinant Protein

source-species:

Species:

source-species:

Recombinant Protein Sequence:

Fusion Tag:

Application Note:

Predicted Molecular Weight:

Purity:

physical-state:

Buffer:

Storage Conditions:

Ncbi Official Symbol:

Additional Names:

Protein Accession Number:

Protein Gi Number:

Ncbi Gene Id Number:

Background:

Disclaimer:

List Size:

Shipping Info

Customize your order

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