GRAP2 Antibody

CATALOG NUMBER: 57-955

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human GRAP2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
38 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GRAP2
Additional Names:
GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, P38, Protein GADS, SH3-SH2-SH3 adapter Mona, GRAP2, GADS, GRB2L, GRID
Protein Accession Number:
O75791
Ncbi Gene Id Number:
9402
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the GRB2/Sem5/Drk family.This member is an adaptor-like protein involved inleukocyte-specific protein-tyrosine kinase signaling. Like itsrelated family member, GRB2-related adaptor protein (GRAP), thisprotein contains an SH2 domain flanked by two SH3 domains. Thisprotein interacts with other proteins, such as GRB2-associatedbinding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2),through its SH3 domains. Transcript variants utilizing alternativepolyA sites exist.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Preisinger, C., et al. Cell. Signal. 22(5):848-856(2010)
Background Reference 3:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 4:
Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-955

List Size:
400 ul

List Price:

$495.00

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