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Western blot analysis of GRB7 Antibody in mouse brain tissue lysates (35ug/lane)
Western blot analysis of GRB7 Antibody in mouse brain tissue lysates (35ug/lane)

GRB7 Antibody

CATALOG NUMBER: 63-960

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GRB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the Central region of human GRB7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GRB7
Additional Names:
Growth factor receptor-bound protein 7, B47, Epidermal growth factor receptor GRB-7, GRB7 adapter protein, GRB7
Protein Accession Number:
Q14451
Protein Gi Number:
116242503
Ncbi Gene Id Number:
2886
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GRB7 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK).
Background Reference 1:
Depetris, R.S., et al. Nat. Struct. Mol. Biol. 16(8):833-839(2009)
Background Reference 2:
Chu, P.Y., et al. J. Biol. Chem. 284(30):20215-20226(2009)
Background Reference 3:
Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)
Background Reference 4:
Bai, T., et al. Carcinogenesis 29(3):473-479(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-960

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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