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Western blot analysis in mouse heart tissue lysates (35ug/lane).
GRIN2A Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in mouse heart tissue lysates (35ug/lane).

GRIN2A Antibody

CATALOG NUMBER: 55-788

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This GRIN2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1057-1084 amino acids from the Central region of human GRIN2A.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
165 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GRIN2A
Additional Names:
Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2A, NMDAR2A
Protein Accession Number:
Q12879
Protein Gi Number:
14285603
Ncbi Gene Id Number:
2903
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
N-methyl-D-aspartate (NMDA) receptors are a class ofionotropic glutamate-gated ion channels. These receptors have beenshown to be involved in long-term potentiation, anactivity-dependent increase in the efficiency of synaptictransmission thought to underlie certain kinds of memory andlearning. NMDA receptor channels are heteromers composed of the keyreceptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) andNMDAR2D (GRIN2D). Alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
Background Reference 1:
Endele, S., et al. Nat. Genet. 42(11):1021-1026(2010)
Background Reference 2:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 3:
Saus, E., et al.Psychiatr Res 44(14):971-978(2010)
Background Reference 4:
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-788

List Size:
400 ul

List Price:

$495.00

Datasheet
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