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Western blot analysis of extracts from Mouse brain cells using GRIN2B (Phospho-Ser1303) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from Mouse brain cells using GRIN2B (Phospho-Ser1303) Antibody. The lane on the right is treated with the antigen-specific peptide.

GRIN2B (phospho Ser1303) Antibody

CATALOG NUMBER: 79-930

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
GRIN2B (phospho Ser1303) antibody was raised against a peptide sequence around phosphorylation site of Serine 1303 (Q-H-S (p)-Y-D) derived from Human GRIN2B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of GRIN2B only when phosphorylated at serine 1303.
Predicted Molecular Weight:
170 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
GRIN2B
Additional Names:
GRIN2B, NMDE2, NME2, NR2B, NR3
Protein Accession Number:
NP_000825.2
Protein Gi Number:
4504127
Ncbi Gene Id Number:
2904
Background:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
Background Reference 1:
Adams S.L., Biochim. Biophys. Acta 1260:105-108(1995).
Background Reference 2:
Hess S.D., J. Pharmacol. Exp. Ther. 278:808-816(1996).
Background Reference 3:
Mandich P., Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-930

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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