GTF2B Antibody

CATALOG NUMBER: 57-669

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Immunogen:
This GTF2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human GTF2B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
35 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GTF2B
Additional Names:
Transcription initiation factor IIB, General transcription factor TFIIB, S300-II, GTF2B, TF2B, TFIIB
Protein Accession Number:
Q00403
Protein Gi Number:
135629
Ncbi Gene Id Number:
2959
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the general transcription factor IIB,one of the ubiquitous factors required for transcription initiationby RNA polymerase II. The protein localizes to the nucleus where itforms a complex (the DAB complex) with transcription factors IIDand IIA. Transcription factor IIB serves as a bridge between IID,the factor which initially recognizes the promoter sequence, andRNA polymerase II.
Background Reference 1:
Wang, Y., et al. Curr. Biol. 20(6):548-553(2010)
Background Reference 2:
Thompson, N.E., et al. J. Biol. Chem. 284(37):24754-24766(2009)
Background Reference 3:
Gilman, B., et al. J. Biol. Chem. 284(14):9093-9098(2009)
Background Reference 4:
Vogt, C., et al. J. Virol. 82(22):11446-11453(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-669

List Size:
400 ul

List Price:

$495.00

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