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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

GTF2IRD1 Antibody

CATALOG NUMBER: 59-658

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GTF2IRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human GTF2IRD1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
106 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GTF2IRD1
Additional Names:
General transcription factor II-I repeat domain-containing protein 1, GTF2I repeat domain-containing protein 1, General transcription factor III, MusTRD1/BEN, Muscle TFII-I repeat domain-containing protein 1, Slow-muscle-fiber enhancer-binding protein, USE B1-binding protein, Williams-Beuren syndrome chromosomal region 11 protein, Williams-Beuren syndrome chromosomal region 12 protein, GTF2IRD1
Protein Accession Number:
Q9UHL9
Protein Gi Number:
21263630
Ncbi Gene Id Number:
9569
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene contains five GTF2I-likerepeats and each repeat possesses a potential helix-loop-helix(HLH) motif. It may have the ability to interact with otherHLH-proteins and function as a transcription factor or as apositive transcriptional regulator under the control ofRetinoblastoma protein. This gene plays a role in craniofacial andcognitive development and mutations have been associated withWilliams-Beuren syndrome, a multisystem developmental disordercaused by deletion of multiple genes at 7q11.23. Alternativesplicing results in multiple transcript variants. [provided byRefSeq].
Background Reference 1:
Antonell, A., et al. J. Med. Genet. 47(5):312-320(2010)
Background Reference 2:
Palmer, S.J., et al. J. Biol. Chem. 285(7):4715-4724(2010)
Background Reference 3:
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Background Reference 4:
Dai, L., et al. Am. J. Med. Genet.149A (3), 302-314 (2009) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-658

List Size:
400 ul

List Price:

$495.00

Datasheet
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